The story
Why Replenexists.
The injection does its job. Your appetite shrinks and the weight goes. So do the things a full plate used to bring: protein, fiber, water, minerals. The founder kept seeing it in people close by in Bali. This is what we built for it.
Every number sourcedEvery ingredient namedNo miracle claims
What the injection changes
Less on the plate, every day.
of the weight lost is lean mass, not fat, unless protein and training keep it.
Body composition review, 2025protein per kilo a day, the target of the 2025 clinical advisory.
American Journal of Clinical Nutrition, 2025Less food means less protein, fiber, water, minerals and vitamins, every day. Replen puts them back, in servings you can finish.
What people go through
The side effects nobody plans for.
Ask anyone a month in. The first weeks bring nausea, a gut that stops, or the opposite: nausea, constipation, diarrhea and vomiting are the most reported side effects in the big trials (STEP 1, SURMOUNT-1). The slow ones arrive later. Flat energy. A headache on day three. Muscle leaving with the fat. Hair on the pillow months after. Here is what people describe, and what helps.
Full after four bites.
You still need 1.2 to 1.6 g of protein per kilo a day, and a 300 ml creamy shake sits like a brick. What helps: 200 ml, thin as juice, with 20 g of protein in it. Two or three sips at a time is fine.
The gut slows down.
The injection slows your stomach on purpose. Thick fibers like psyllium slow it more, and nobody has tested the two together. What helps: a gentle fiber that does not thicken, magnesium, water, and half a serving to start.
The day-three headache.
Less food is also less water and fewer minerals. People describe a dull headache on day three of a new dose. What helps: sodium, potassium and magnesium in the water you do drink, first thing.
A stomach that turns.
Nausea and sulfur burps, worst after a dose increase or a fatty meal. What helps: ginger has moderate to strong evidence against nausea in general, none yet with these injections, and we say so.
Lean mass goes with the fat.
Of every ten kilos lost, two to three are lean mass, and you want to keep it. What helps: enough protein, strength training, and creatine, which has decades of evidence for keeping muscle.
Bone thins quietly.
A 2024 trial found semaglutide lowered hip and spine bone density within a year, with more breakdown and no extra building. What helps: calcium, vitamin D3 and K2, and strength training. No trial has tested them on the injection yet, and we say so.
Hair sheds months later.
Fast weight loss pushes hair into a resting phase. It usually grows back. Nothing in a pack fixes that, and we will not pretend it does. Enough protein and nutrients, month after month, is the honest support.
| The data | Why it matters | What is in Replen for it |
|---|---|---|
| 500 to 650fewer calories a day on the injectionNature Medicine, 2025 | Less food means fewer chances for protein, vitamins and minerals. | 20 g protein, 6 vitamins, zinc and magnesium in the morning pack. |
| 20 to 30 percentof the weight lost is lean mass, up to 45 percent in one STEP 1 calculationBody composition review, 2025 | Not everything you lose is fat. | 20 g protein and 1.5 g leucine in the morning, 3 g creatine at night. |
| 25 to 44 percentget nauseaUS prescribing information, pooled trials | Eating and drinking enough gets harder. | Thin drinks you can sip, and 500 mg ginger in the morning pack. Ginger has evidence against nausea in general, none yet with the injections. |
| 19 to 30 percentget diarrheaUS prescribing information, pooled trials | Fluids and electrolytes go with it. | Sea salt, coconut water and marine magnesium in 200 ml. |
| 11 to 24 percentget constipationUS prescribing information, pooled trials | Less food is less fiber, and the injection slows the gut. | 5 g gentle guar bean fiber and 150 mg magnesium citrate at night. |
| 8 to 24 percentvomitUS prescribing information, pooled trials | Hydration gets harder still. | Electrolytes in the morning glass, warm water at night. |
| 1.2 to 1.6 gprotein per kilo of body weight a day is the targetAJCN joint advisory, 2025 | Hard to reach with a small appetite. | 20 g in one 200 ml glass, thin and fruity. |
The symptom ranges span the two main weight-loss injections as reported in their US prescribing information (pooled placebo-controlled trials, 2021 and 2023); in the placebo groups 2 to 16 percent reported the same symptoms. Replen is food. It does not treat these side effects and does not replace your doctor's advice. Planned formula; final amounts are printed on the pack.
Why we made it
Give back what the injection takes.
"A GLP-1's best friend. So many people take it, and more will. But their bodies are missing things. I want to give back what it takes from them, from nature, in a good way."
The founder, Bali
We are not against the injection. We are for the person taking it. The honest version: the injection does not pull nutrients out of you. It makes you eat 500 to 650 fewer calories a day, so protein, fiber, water, minerals and vitamins fall short, and 20 to 30 percent of the weight you lose is lean mass, not fat. Replen puts those back, from sources you can name, in servings a small appetite can finish.
Ingredients you can follow
Every ingredient has a source you can name.
No blends, no hidden amounts. The supplier and country of origin of every ingredient are published with the first batch, together with the lab report.
20 g protein, morning
Filtered from milk into a clear, fruity protein, with 1.5 g leucine added. Not creamy.
Electrolytes, morning
Sea salt for about 400 mg sodium, coconut water powder and magnesium from seawater.
Thiamine and six vitamins, morning
A real thiamine dose for the vomiting weeks, with D3, B6, B12, folate, C from acerola cherry and zinc at daily-value levels.
500 mg ginger, morning
Ginger root, and ginger with chamomile as the night flavor.
5 g fiber, night
Partially hydrolysed guar gum from the guar bean, a low-viscosity fiber chosen because it is gentle on a slowed stomach.
150 mg magnesium, night
Magnesium citrate, the form usually picked for the gut.
3 g creatine, night
Made synthetically, not from animals. We use it because the evidence for muscle is strong.
250 mg calcium and K2, night
Fast weight loss costs bone, a 2024 trial measured it on semaglutide. Calcium and K2 at night, D3 in the morning.
Kiwifruit extract, night
The fruit with two constipation trials behind it, next to the fiber.
Planned formula. Final amounts are set with the manufacturer and printed on the pack. The full list with form, amount and where it is found in food.
Questions
Asked most often.
Why do people lose muscle on the injection?
Because they eat far less and often too little protein. In the trials 20 to 30 percent of the weight lost was lean mass, up to 45 percent in one calculation. Enough protein, strength training and creatine are what keeps it.
Why does hair fall out months after starting?
Fast weight loss pushes hair into a resting phase; the shedding shows up months later and usually grows back. No powder fixes it. Enough protein and nutrients over months is the honest support.
What helps with nausea on the injection?
Small, thin drinks instead of big creamy shakes, and ginger, which has moderate to strong evidence against nausea in general, none yet with these injections. Ask your doctor if it does not settle.
Is Replen a treatment for these side effects?
No. Replen is food: the protein, fiber, minerals and vitamins a small appetite skips. It does not treat, cure or prevent anything and does not replace your doctor's advice or your medication.
Founding round
Built with the first 300.
The first 300 taste the pilot batch before anyone else, vote on the flavors and the pack size, and see every batch test result first. A refundable deposit of 25 USD holds a spot, with 25 percent off the first box.
